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Protein-Based Diagnostics focuses on antibodies: what they are, where they come from and how they work. A prominent example of an established diagnostic marker is the glycated protein species of hemoglobin, termed HbA1c.
Proximity ligation assay (PLA) is a unique method in which single-stranded oligonucleotides are conjugated to affinity binders of proteins, followed by amplification of the signal by DNA polymerization and hybridization of complementary oligonucleotides labeled with fluorogenic or chromogenic readout.